Universtiy of Miami Miller School of Medicine Graduate Studies

Course Descriptions

The following is a list of specific Cellular Physiology and Molecular Biophysics course descriptions. Please see the First Year Program in Biomedical Sciences for other required courses as well as the other graduate program pages for elective options.

PHS 610 – Cell Physiology

General principles of cell physiology, chemical and physical structure of membranes, membrane transport and electrical phenomena, action potentials, muscle contraction, energy transduction, nerve impulse conduction and synaptic transmission.

PHS 611 – Neurophysiology

Physiology of the mammalian nervous system. 

PHS 612 – Systemic Physiology

Physiology of the mammalian cardiovascular, respiratory, and renal systems.

PHS 741 – Principles of Membrane Physiology and Biophysics I

Chemical and physical structure of membranes; model systems; permeability and transport; membrane potential; ionic channels; excitability in nerve and muscle; ionophores; active transport; membrane receptors. Same as MCP 741. Prerequisite: CHM 361, BMB 506 and permission of graduate studies.

PHS 742 – Principles of Membrane Physiology and Biophysics II

Osmosis and cell volume; tracer analysis of permeability and compartmentation; theory of channels and carriers; cable properties; Hodgkin-Huxley formalism; Na, K and Ca ion channels; regulation of cellular Na, Ca activities; single-channel analysis; chemical synapses; membrane receptors; cell junctions; excitation and E-C coupling in muscle.
Same as MCP 742. Prerequisite: PHS 641.

PHS 763 – Developmental Neurobiology

Development of the nervous system in all its aspects: origins of neurons and glia; nerve cell differentiation; cellular interactions during neurogenesis; formation of synaptic connections and neuronal circuits; development of nervous functions and ontogeny of behavior; mechanisms of repair and reorganization in the nervous systems; and theories of neuronal plasticity.

PHS 768 – Neuropharmacology

An intensive seminar course for advanced students covering the mechanism of action of drugs on basic neural processes, including action potentials, neurotransmission (storage, release, reception and metabolism of transmitters), and central nervous activity, taught jointly by staff members of Pharmacology and Physiology/Biophysics.

PHS 769 – Nerve and Synapse

An advanced seminar course in the basic mechanisms underlying the propagated nerve impulse and synaptic transmission, including second messengers, neuromodulation, memory mechanisms, and integrative mechanisms underlying behavior.

PHS 780 – Research Ethics

The NIH Guide for Grants and Contracts stipulates that Institutions receiving support for National Research Service Award Training Grants are required to develop a program in the principles of Scientific Integrity. This program should be an integral part of the proposed training effort. The University of Miami School of Medicine has chosen to respond to this requirement with this course. This course must be taken during the first semester in the Program. This is a six-hour course and will be given in two sessions of three hours each. Prerequisite: Permission of the graduate advisor or program director.

PHS 830 – Dissertation Research-Pre-Candidacy

Required for all PhD candidates. The student will enroll for credits as determined by the Office of Graduate Studies but not less than a total of 24. No more than 12 hours of research may be taken in a regular semester, and no more than six in a summer session.

PHS 840 – Doctoral Dissertation-Post Candidacy

Required for all PhD candidates. The student will enroll for credits as determined by the Office of Graduate Studies.
h3. PHS 850 – Research in Residence

Student must be registered in the semester they plan to defend. Used to establish research in residence for the PhD after the student has been enrolled for the permissible cumulative total in appropriate doctoral research. Credit is not granted. Student may be regarded as full-time residence as determined by the Dean of the Graduate School.